Helminth infection-induced carcinogenesis: spectrometric insights from the liver flukes, Opisthorchis and Fasciola

The Liver Flukes: Clonorchis sinensis, Opisthorchis spp, and Metorchis spp

Endemicity of Opisthorchis viverrini Liver Flukes, Vietnam, 2011–2012

Technical Appendix Table 1. Prevalence and intensity of Opisthorchis viverrini fluke metacercariae in fish collected in several districts of Phu Yen province,Vietnam Fish species Collection site district/ commune Prevalence, % (No. infected/total no. examined) Infection intensity (metacercariae/fish) Type of water body Other zoonotic metacercaria infections* Crucian carp (Carasius auratus) *No ...

Infection with Liver Flukes

of hepatic aflatoxIn Bi and N-nitrosodiethylamine in infected males and 20-40% in infected females (Kirby et al., 1994). Immunohistochemical analysis of aflatoxIn Bi-DNA adducts in parasitized animaIs indicated that the greatest numbers of adducts occurred in the regions of highest CYP2A activity. Studies with a related liver fluke, Fasciola hepatica, also showed enhanced cyochrome P450-related...

Comparative Characterization of MicroRNAs from the Liver Flukes Fasciola gigantica and F. hepatica

MicroRNAs (miRNAs) are key regulators of gene expression at the post-transcription level. The present study specifically explored and compared the miRNA expression profiles of F. gigantica and F. hepatica using an integrated sequencing and bioinformatics platform and quantitative real-time PCR. Nineteen and 16 miRNA candidates were identified from F. gigantica and F. hepatica, respectively. The...

Bioaccumulation of Some Heavy Metals in the Liver Flukes Fasciola hepatica and F. gigantica

BACKGROUND Heavy metals tend to bioaccumulate in living organisms, and their accumulation has been a major concern. As mammals are known to excrete heavy metals via their bile, it seems to be very promising to analyse metal burdens of parasites that infect the biliary tree such as liver flukes of the genus Fasciola. The present study was carried out to evaluate F. hepatica and F. gigantica as b...